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Tag: ACE-I

UncategorizedPosted onMarch 31, 2020

Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19

• ACE2, an enzyme that physiologically counters RAAS activation, is the functional receptor to SARS-CoV-2, the virus responsible for the Covid-19 pandemic • Select preclinical…

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UncategorizedPosted onMarch 23, 2020

ACE2 in SARS. RAAS blockade may help

Paper describing experiments showing ARB reduced SARS-CoV-induced disease in mouse model. Trial of ARBs for SARS-CoV-2 (COVID19) registered NCT04312009

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UncategorizedPosted onMarch 22, 2020

ACE2 is the SARS COV-2 receptor required for cell entry

NEJM Jwatch with references: Although offering a promising therapeutic and vaccine target against SARS-CoV-2, these new findings remind us that the viral pathogenesis of COVID-19…

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UncategorizedPosted onMarch 18, 2020

Summary of ACEi/ARB recommendations

Table collating recommendations from the various countries societies on use of ACEi/ ARB – all essentially recommend continuation

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UncategorizedPosted onMarch 18, 2020

The Coronavirus Conundrum: ACE2 and Hypertension Edition

There has been an unprecedented interest in this topic. Hence we have added more details and moved this section from the main page to a…

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UncategorizedPosted onMarch 17, 2020

Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?

We suggest that patients with cardiac diseases, hypertension, or diabetes, who are treated with ACE2-increasing drugs, are at higher risk for severe COVID-19 infection and,…

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