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UncategorizedPosted onMay 18, 2020

Tracking the COVID-19 pandemic in Australia using genomics

BACKGROUND: Whole-genome sequencing of pathogens can improve resolution of outbreak clusters and define possible transmission networks. We applied high-throughput genome sequencing of SARS-CoV-2 to 75%…

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UncategorizedPosted onMay 17, 2020

Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series

Although patients in our study presented with predominately mild, non-specific symptoms, infectiousness before or on the day of symptom onset was substantial. Additionally, the incubation…

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UncategorizedPosted onMay 17, 2020

The duty to treat: where do the limits lie?

Doctors are dying. The combination of a novel virus, no treatment, and inadequate supplies of personal protective equipment (PPE) is putting frontline health workers at…

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UncategorizedPosted onMay 16, 2020

The potential danger of suboptimal antibody responses in COVID-19

There is a desperate need for effective therapies and vaccines for SARS-CoV-2 to mitigate the growing economic crisis that has ensued from societal lockdown. Vaccines…

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UncategorizedPosted onMay 16, 2020

Novel Percutaneous Tracheostomy for Critically Ill Patients with COVID-19

Patients with severe COVID-19 that were on mechanical ventilation ≥ 5 days were evaluated for percutaneous dilational tracheostomy. We developed a novel percutaneous tracheostomy technique…

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UncategorizedPosted onMay 14, 2020

Airborne transmission of severe acute respiratory syndrome coronavirus‐2 to healthcare workers: a narrative review

Healthcare workers are at risk of infection during the severe acute respiratory syndrome coronavirus‐2 pandemic. International guidance suggests direct droplet transmission is likely and airborne…

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UncategorizedPosted onMay 14, 2020

Speech droplets generated by asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are in- creasingly considered to be a likely mode of disease transmission. Highly sen

Speech droplets generated by asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are increasingly considered to be a likely mode of disease transmission.…

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UncategorizedPosted onMay 14, 2020

Performance of the rapid Nucleic Acid Amplification by Abbott ID NOW COVID-19 in nasopharyngeal swabs transported in viral media and dry nasal swabs, in a New York City academic institution

The recent emergence of the SARS-CoV-2 pandemic has posed formidable challenges for clinical laboratories seeking reliable laboratory diagnostic confirmation. The swift advance of the crisis…

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UncategorizedPosted onMay 7, 2020May 7, 2020

Interpreting Diagnostic Tests for SARS-CoV-2

The pandemic of coronavirus disease 2019 (COVID-19) continues to affect much of the world. Knowledge of diagnostic tests for severe acute respiratory syndrome coronavirus 2…

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UncategorizedPosted onMay 7, 2020

Hyperinflammatory shock in children during COVID-19 pandemic

South Thames Retrieval Service in London, UK, provides paediatric intensive care support and retrieval to 2 million children in South East England. During a period…

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UncategorizedPosted onMay 7, 2020

Household Secondary Attack Rate of COVID-19 and Associated Determinants

Background: As of April 2, 2020, the global reported number of COVID-19 cases has crossed over 1 million with more than 55,000 deaths. The household…

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UncategorizedPosted onMay 7, 2020

Age specificity of cases and attack rate of novel coronavirus disease (COVID-19)

Age distribution of the cases with novel coronavirus disease (COVID-19) is rather different from that of influenza. We examined the age distribution of COVID-19 cases…

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UncategorizedPosted onMay 3, 2020

Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility

Twenty-three days after the first positive test result in a resident at this skilled nursing facility, 57 of 89 residents (64%) tested positive for SARS-CoV-2.…

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UncategorizedPosted onMay 2, 2020

Cluster of COVID-19 in northern France: A retrospective closed cohort study

Background: The Oise department in France has been heavily affected by COVID-19 in early 2020. Methods: Between 30 March and 4 April 2020, we conducted…

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UncategorizedPosted onMay 2, 2020

Shedding of infectious SARS-CoV-2 in symptomatic neonates, children and adolescents

Children are underrepresented in COVID-19 case numbers, with most pediatric cases exhibiting limited severity, and do not seem to be major drivers of transmission, unlike…

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